- CasNo 324763-46-4
- Purity 99%
Location:Home > Pharmaceutical
5(S)-[1(S)-Azido-3(S)-[4-methoxy-3-(3-methoxypropoxy)benzyl]-4-methylpentyl]-3(S)-isopropyldihydrofuran-2-one
Factory Sells Best Quality 5(S)-[1(S)-Azido-3(S)-[4-methoxy-3-(3-methoxypropoxy)benzyl]-4-methylpentyl]-3(S)-isopropyldihydrofuran-2-one 324763-46-4 with steady supply
- Molecular Formula: C25H39N3O35
- Molecular Weight: 461.602
- Vapor Pressure: 0Pa at 20℃
- PSA: 103.74000
- Density: 1.19g/cm3 at 20℃
- LogP: 5.03466
5(S)-[1(S)-Azido-3(S)-[4-methoxy-3-(3-methoxypropoxy)benzyl]-4-methylpentyl]-3(S)-isopropyldihydrofuran-2-one(Cas 324763-46-4) Usage
InChI:InChI=1/C25H39N3O5/c1-16(2)19(14-21(27-28-26)23-15-20(17(3)4)25(29)33-23)12-18-8-9-22(31-6)24(13-18)32-11-7-10-30-5/h8-9,13,16-17,19-21,23H,7,10-12,14-15H2,1-6H3/t19-,20-,21-,23-/m0/s1
324763-46-4 Relevant articles
A aliskiren or its salt separation and analysis method
-
, (2017/08/25)
The invention relates to a separation an...
SYNTHESIS OF ALISKIREN
-
, (2012/05/05)
The present invention provides novel pro...
A total synthesis of aliskiren
Nam, Gyeok,Ko, Soo Y.
, p. 1937 - 1945,9 (2012/12/12)
A total synthesis of aliskiren (20) was ...
AMIDE INHIBITORS OF RENIN
-
, (2010/06/13)
The present invention relates to new ami...
324763-46-4 Process route
-
-
393108-57-1
(3S,5S)-5-{(1R,3S)-1-bromo-3-{[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl}-4-methylpentyl}-dihydro-3-(1-methylethyl)furan-2(3H)-one
-
-
324763-46-4
(3S,5S)-5-{(1S,3S)-1-azido-3-{[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl}-4-methylpentyl}-dihydro-3-(1-methylethyl)furan-2(3H)-one
| Conditions | Yield |
|---|---|
|
With
sodium azide;
In
N,N-dimethyl-formamide;
at 90 ℃;
for 48h;
stereoselective reaction;
|
35%
|
|
With
sodium azide;
In
2,2'-[1,2-ethanediylbis(oxy)]bisethanol;
at 90 ℃;
for 72h;
Inert atmosphere;
|
132 g
|
-
-
393108-57-1
C25 H39 BrO5
-
-
324763-46-4
(3S,5S)-5-{(1S,3S)-1-azido-3-{[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl}-4-methylpentyl}-dihydro-3-(1-methylethyl)furan-2(3H)-one
| Conditions | Yield |
|---|---|
|
With
sodium azide; Aliquat 336;
In
water;
at 75 - 80 ℃;
for 48h;
|
324763-46-4 Upstream products
-
325740-68-9
Methanesulfonic acid (1R,3S)-1-((2S,4S)-4-isopropyl-5-oxo-tetrahydro-furan-2-yl)-3-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-4-methyl-pentyl ester
-
387353-75-5
4-Bromo-benzenesulfonic acid (1R,3S)-1-((2S,4S)-4-isopropyl-5-oxo-tetrahydro-furan-2-yl)-3-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-4-methyl-pentyl ester
-
145589-03-3
(S)-4-benzyl-3-(3-methylbutanoyl)oxazolidin-2-one
-
191152-27-9
(3S,5S)-5-Hydroxymethyl-3-isopropyl-dihydro-furan-2-one
324763-46-4 Downstream products
-
324763-47-5
(2S,4S,5S,7S)-N-(3-amino-2,2-dimethyl-3-oxopropyl)-5-azido-4-hydroxy-2-isopropyl-7-(4-methoxy-3-(methoxypropoxy)benzyl)-8-methylnonanamide
-
173334-57-1
(2S,4S,5S,7S)-5-Amino-4-hydroxy-2-isopropyl-7-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-8-methyl-nonanoic acid (2-carbamoyl-2-methyl-propyl)-amide
-
909406-55-9
5-azido-4-hydroxy-2-isopropyl-7-[4-methoxy-3-(3-methoxypropoxy)benzyl]-8-methylnonanoic acid (1-methylpiperidin-4-yl)amide
-
890796-80-2
N-phenyl-5(S)-azido-4(S)-hydroxy-2(S)-isopropyl-7(S)-[4-methoxy-3-(3-methoxypropoxy)benzyl]-8-methylnonanamide
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