- CasNo83930-13-6
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What is the GRF (1-44) (HUMAN) ?
GRF (1-44) (HUMAN) is powder, while it's Molecular Formula is C215H358N72O66S. Used in Pharmaceutical Industry:
GRF (1-44) (HUMAN) is used as a pharmaceutical agent for the treatment of growth disorders and conditions related to growth hormone deficiency. It helps stimulate the release of growth hormone, promoting growth and development in individuals with growth-related issues.
Used in Research Applications:
GRF (1-44) (HUMAN) is used as a research tool in the study of growth hormone regulation, pituitary function, and the role of GHRH in various physiological processes. It aids researchers in understanding the mechanisms of growth hormone release and its impact on overall health and well-being.
What is the CAS number for GRF (1-44) (HUMAN) ?
The CAS number of GRF (1-44) (HUMAN) is 83930-13-6.
More information of GRF (1-44) (HUMAN) 83930-13-6 are:
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Synonyms |
(1-44)HumanGH-releasing factor; 1-44-Human pancreatic GH-releasing factor; 1-44-Humansomatoliberin; 1: PN: WO2006042408 SEQID: 3 claimed protein; Human growthhormone-releasing factor; Human growth hormone-releasing factor(1-44); Humangrowth hormone-releasing hormone; Human growth hormone-releasing hormone (1-44)amide; Human growth hormone-releasing hormone(1-44); Human pancreatic growthhormone-releasing factor (1-44); Human pancreatic growth hormone-releasingfactor-44; Human pancreatic islet somatoliberin; Human pancreaticsomatoliberin; Human pancreatic somatoliberin(1-44) amide; Humansomatoliberin(1-44) amide; L-Leucinamide, L-tyrosyl-L-alanyl-L-a-aspartyl-L-alanyl-L-isoleucyl-L-phenylalanyl-L-threonyl-L-asparaginyl-L-seryl-L-tyrosyl-L-arginyl-L-lysyl-L-valyl-L-leucylglycyl-L-glutaminyl-L-leucyl-L-seryl-L-alanyl-L-arginyl-L-lysyl-L-leucyl-L-leucyl-L-glutaminyl-L-a-aspartyl-L-isoleucyl-L-methionyl-L-seryl-L-arginyl-L-glutaminyl-L-glutaminylglycyl-L-a-glutamyl-L-seryl-L-asparaginyl-L-glutaminyl-L-a-glutamyl-L-arginylglycyl-L-alanyl-L-arginyl-L-alanyl-L-arginyl-;SM 8144; Somatoliberin (human hypothalamus); Somatoliberin (human);Somatorelin; human GH-releasing hormone (1-44)-NH2 |
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CAS?Number |
83930-13-6 |
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Molecular Formula |
C215H358N72O66S |
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Molecular Weight |
5039.65 |
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PSA |
2361.59000 |
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LogP |
3.11270 |
What is GRF (1-44) (HUMAN) (83930-13-6) used for?
GHRH is expressed and secreted from the hypothalamic neurons of the arcuate nucleus (ARC). GHRH stimulates the release of growth hormone (GH) in the anterior pituitary. In 1982, three isoforms of GHRH(1–37, 1–40, 1–44 aa residues) were initially isolated from human pancreatic tumors that caused acromegaly, and the latter two were found in the human hypothalamus. The aa sequence of GHRH was also identified in various vertebrates from rodents to fish, including a protochordate. In nonmammalian vertebrates, GHRH-like peptide (pituitary adenylate cyclase-activating polypeptide (PACAP)-related peptide in mammals) was first isolated like GHRH, although the GHRH-like peptide had less activity on GH release. Later, actual GHRH, which was more phylogenetically and structurally similar to mammalian GHRH and showed GH-releasing activity, was isolated in nonmammalian vertebrates.
InChI:InChI=1/C215H358N72O66S/c1-24-106(15)166(285-174(318)112(21)251-193(337)145(91-163(309)310)270-173(317)109(18)249-175(319)119(218)86-115-49-53-117(293)54-50-115)208(352)278-142(87-114-39-27-26-28-40-114)200(344)287-168(113(22)292)209(353)279-144(90-157(225)301)199(343)283-150(99-291)204(348)274-141(88-116-51-55-118(294)56-52-116)197(341)261-126(47-37-78-243-214(235)236)181(325)260-122(42-30-32-73-217)192(336)284-165(105(13)14)206(350)277-137(82-101(5)6)178(322)247-95-160(304)253-129(58-65-152(220)296)185(329)272-140(85-104(11)12)196(340)282-147(96-288)202(346)252-111(20)172(316)256-124(45-35-76-241-212(231)232)180(324)259-121(41-29-31-72-216)184(328)271-139(84-103(9)10)195(339)273-138(83-102(7)8)194(338)266-133(61-68-155(223)299)190(334)276-146(92-164(311)312)201(345)286-167(107(16)25-2)207(351)268-135(71-80-354-23)191(335)281-148(97-289)203(347)262-127(48-38-79-244-215(237)238)182(326)264-131(59-66-153(221)297)187(331)263-128(57-64-151(219)295)177(321)246-94-159(303)254-130(62-69-161(305)306)186(330)280-149(
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