- CasNo 97682-44-5
- Purity 99%
Location:Home > Pharmaceutical
Quality products?make an important contribution to long-term revenue and profitability. Factory supply Irinotecan 97682-44-5 with low price
1.What is the Irinotecan ?
Irinotecan is a topoisomerase I inhibitor for LoVo cells and HT-29 cells with IC50 of 15.8 μM and 5.17 μM, respectively
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143254-82-4
4-piperidinopiperidine-1-carbonyl chloride hydrochloride
-
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86639-52-3,110714-48-2,130144-34-2,113015-38-6,647852-82-2
7-ethyl-10-hydroxycamptothecin
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97682-44-5,130144-33-1
irinotecan
Conditions
| Conditions | Yield |
|---|---|
|
With
dmap;
In
acetonitrile;
at 75 ℃;
for 5h;
Sonication;
|
94.3%
|
|
With
N,N-dimethyl-ethanamine;
In
dichloromethane;
at 20 ℃;
for 2.5h;
Reagent/catalyst;
Solvent;
|
91%
|
|
With
pyridine;
In
dichloromethane;
for 2h;
Inert atmosphere;
Schlenk technique;
|
81%
|
|
With
1-Methylpyrrolidine;
In
dichloromethane;
at 20 - 45 ℃;
|
-
-
103816-19-9
4-piperidinopiperidine-1-carbonyl chloride
-
-
86639-52-3,110714-48-2,130144-34-2,113015-38-6,647852-82-2
7-ethyl-10-hydroxycamptothecin
-
-
97682-44-5,130144-33-1
irinotecan
Conditions
| Conditions | Yield |
|---|---|
|
With
pyridine; acetamide; triethylamine;
In
dichloromethane;
at 30 - 40 ℃;
for 2h;
Product distribution / selectivity;
Inert atmosphere;
|
95%
|
|
With
pyridine;
In
acetamide; dichloromethane;
at 30 - 40 ℃;
for 2h;
Product distribution / selectivity;
Inert atmosphere;
|
95%
|
|
|
89%
|
|
With
1,4-diaza-bicyclo[2.2.2]octane; N-ethyl-N,N-diisopropylamine;
In
dichloromethane;
at 35 - 40 ℃;
for 0.5h;
Product distribution / selectivity;
|
88%
|
|
With
sodium hydrogencarbonate;
In
pyridine; chloroform;
|
63.5%
|
|
With
pyridine;
at 20 ℃;
for 1h;
|
63.5%
|
|
With
pyridine;
Yield given;
|
|
|
In
pyridine;
at 20 - 25 ℃;
for 2h;
|
|
|
4-piperidinopiperidine-1-carbonyl chloride; 7-ethyl-10-hydroxycamptothecin;
With
pyridine;
In
dichloromethane;
With
sodium hydrogencarbonate;
In
dichloromethane; water;
|
|
|
With
pyridine;
at 40 ℃;
for 2h;
Product distribution / selectivity;
|
|
|
With
pyridine;
for 6 - 12h;
|
|
|
With
pyridine; triethylamine;
at 20 ℃;
for 2h;
Inert atmosphere;
|
2.What is the CAS number for Irinotecan ?
The CAS number of Irinotecan is 97682-44-5.
More information of Irinotecan 97682-44-5 are:
|
CAS?Number |
97682-44-5 |
|
Density |
1.4 g/cm3 |
|
Melting Point |
222-223° |
|
Boiling Point |
873.4 °C at 760 mmHg |
|
Flash Point |
482 °C |
|
PSA |
114.20000 |
|
LogP |
3.96690 |
|
Pka |
11.20±0.20(Predicted) |
3.What are another words for Irinotecan ?
Synonyms?for?Irinotecan 97682-44-5:[1,4'-Bipiperidine]-1'-carboxylic acid,(4S)-4,11-diethyl-3,4,12,14-tetrahydro- 4-hydroxy-3,14-dioxo-1H-pyrano[3',4':6,7]- indolizino[1,2-b]quinolin-9-yl ester;(+)-Irinotecan;Irinotecan base;Irinotecanum [INN-Latin];Irrotecan hydrochloride;1,4'-bipiperidine-1'-carboxylic acid (s)-4,11-diethyl-3,4,12,14- tetrahydro-4-hydroxy-3,14-dioxo-1h-pyrano[3',4':6,7]indolizino[1,2-b]quinolin -9-yl ester;Irinotecan HCL;Irinotecan(TECANS);
4.What is the molecular formula of Irinotecan?
The chemical formula of ?Irinotecan is?C33 H38 N4 O6 which containing 33 Carbon atoms,38 Hydrogen atoms,4 Nitrogen atoms and 6 Oxygen atoms,and the molecular weight of??Irinotecan?is 586.688.
5.What is Irinotecan (97682-44-5) used for?
Irinotecan is a pentacyclic alkaloid with the chemical name 7-ethyl-10-[4-(1-piperidino)-1-piperidino]-carbonyloxycamptothecine. It has a bis-piperidine side chain contributing to its water solubility. Irinotecan belongs to the class of topoisomerase I inhibitors and is used in cancer chemotherapy.
InChI:InChI=1/C33H38N4O6/c1-3-22-23-16-21(43-32(40)36-14-10-20(11-15-36)35-12-6-5-7-13-35)8-9-27(23)34-29-24(22)18-37-28(29)17-26-25(30(37)38)19-42-31(39)33(26,41)4-2/h8-9,16-17,20,41H,3-7,10-15,18-19H2,1-2H3/t33-/m0/s1
Relevant articles related to Irinotecan:
|
Article |
Source |
|
A preparation method of irinotecan hydrochloride (by machine translation) |
- , (2019/06/27) |
|
Irinotecan-cholesterol succinic acid simple lipid ion pair, liposome and preparation method and application thereof |
- Paragraph 0045; 0046; 0047, (2018/10/11) |
6.Buy Irinotecan with the best price .
WUHAN ENTAI TECHNOLOGY DEVELOPMENT CO.,LTD is a quality supplier of Irinotecan. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on Irinotecan 97682-44-5.
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